Members of the Council are chosen to serve based on their extensive experience in the fields of veterinary medicine, laboratory animal science or animal research, and their commitment to humane animal care and use. A. A library service (such as AWIC) can be helpful, but is not required. A. where $x$ is in meters and $t$ is in seconds. A. C. To provide a narrative justifying the use of the animal model based on experimental data. Surgery that penetrates and exposes a body cavity or produces substantial physical impairment is described as what kind of surgery? Which statement about the Occupational Health and Safety Program is false? Which of the following statements is/are TRUE regarding preparation of a mouse for surgery? Thermal support is an important aspect of postoperative support. Background. C. Fetuses must be removed for euthanasia after the dam is euthanized. B. B. Retroorbital blood collection from a mouse performed under anesthesia. Office of Laboratory Animal Welfare (OLAW). Your research must comply with the Guide for the Care and Use of Laboratory Animals if: Your institution receives funds from the National Institutes of Health (NIH). D With an existing policy approved by the IACUC, a change in analgesic agent could be approved by VVC. C. Studies in which animals experiencing pain are allowed to die without pain relief. Biosafety in Microbiological and Biomedical Laboratories, Recombinant DNA inserted into the genome of transgenic mice may NOT be covered by the NIH Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules. All answers are correct. D. The selection of an appropriate euthanasia method should address considerations of humaneness to the animal, safety for the staff and onlookers, and experimental needs. Check all that apply. The researchers and regulatory agencies only Which statement is true about mice in the age range of 6-10 days? Having a selective small molecule tool to interrogate this kinase will help demonstrate that CAMKK2 inhibition can be AAALAC Internationalis a private, nonprofit organization that promotes the humane treatment of animals in science through voluntary accreditation and assessment programs. AAALAC endorses the use of animals to advance medicine and science when there are no non-animal alternatives, and when it is done in an ethical and humane way. Institutions receiving PHS money must follow the "Guide" (OLAW oversight) and those accredited with AAALAC are subject to triannual program review and facility visits. Methods of euthanasia deemed "acceptable with conditions" may require scientific justification before IACUC approval. Lets start with the sandy beaches, warm water, and fantastic weather. Which of the following is NOT an example of reduction per the three Rs of Russell and Burch? Explain why this approach was successful. Conduct reviews of the animal care and use program on a semiannual basis, Institutional Animal Care and Use Committee. This concept represents the beginning of the effort to form an accreditation program for laboratory animal care and use. B According to the AWR (3.81.d. Which of the following is considered a minor change that would not require formal IACUC review and approval? D. Laboratory use of recombinant chemical agents for in vitro work. Which statement is true about the anogenital distance in mice? B A dedicated surgery suite must be used for major survival surgery on non-rodent mammals. C. They become less important If the investigator believes the event is due to misuse, mistreatment, or noncompliance, the details of the incident should be reported to the IACUC (or use another reporting method recommended by their organization), so that the incident can be reviewed and investigated (if warranted). Which of the following activities would EXCLUDE an animal from USDA category B? D. Shares information with other regulatory agencies like U.S. Department of Agriculture (USDA) and Office of Laboratory Animal Welfare (OLAW). Which is a TRUE statement below regarding assessment of pain or distress in mice: A. Accreditation by the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) International has long been trumpeted as being the "gold standard" D An effective IACUC protects both the investigator and organization, while inspiring confidence amongst the general public that animal activities are being performed in an ethical manner. D. A change in surgical anesthetic. B. Some types of changes to an animal protocol can be approved administratively by veterinary verification and consultation. Office of Laboratory Animal Welfare (OLAW) Animal care and use regulations and guidelines require organizations to provide training in which of the following areas? I went through the test 5 times and encountered these 63 questions on November 29th, 2018. Sponsors a voluntary accreditation program for animal care and use programs. D. Food should be withheld prior to surgery, but not water. Who is generally given institutional responsibility for deciding if an individual researcher is properly trained to perform animal procedures, as required by law? A. This is not intended to be a search to support the necessity or purpose of the research. When picking up a mouse from a filter top cage, putting the wire bar lid sideways on the cage is helpful to: Reposition your grasp as you take the mouse out of the cage as it will tend to hold on to the wire bar lid. Determine when emergency IACUC meetings must be scheduled. A. C Sterile surgical techniquethe goal of which is to prevent contamination of the surgical siteis required for major and minor survival surgery. It uses mice to grow hybridoma cells on their peritoneal lining. The five flows in marketing channels discussed in the text are. The IACUC can exempt an animal for scientific reasons. D. History and tactics of animal activist groups (such as PeTA and HSUS). Nonverbal communication is defined as how people communicate with each other without talking or writing. In the 1950s, the Professional Standards Committee of the Animal Care Panel (ACP), now the American Association for Laboratory Animal Science (AALAS), recognized a need for assuring the general public that laboratory animal research was conducted on a professional level, and that standard procedures were applied. What is NOT a recommendation for postoperative care of mice? A. A. Which of the statements concerning blood collection in mice and rats is TRUE? BB creams are all-in-one beauty products that can With so many things to do in Miami, youll be able to create the perfect vacation package. D. It is unacceptable to decapitate neonates with scissors, even with IACUC approval. C. Survival Using appropriate personal protective equipment can reduce the risk of allergies to mouse urine and pelt proteins. However, hard inquiriesthose that are made because you applied for more To convert any value in liters to gallons [liquid], just multiply the value in liters by the conversion factor 0.26417205235815. Typically, subcutaneous injections in mice: Which type of bedding is recommended for use in postoperative housing for mice? D. Rabbits are not allowed to be used for antibody production. Blood collection from a superficial vessel of a dog. B. However, the latter should be performed under anesthesia and is not a preferred site because of the potential for damage to the eye when the technique is not done properly or when used repeatedly. IACUCs may allow quick decapitation with scissors for euthanasia of altricial rodent neonates (up to ten days of age). Assessment of wound repair is the only objective of post-operative monitoring. B. Which of the following are NOT allowed by USDA? While restraining a mouse, a technician should check for which of the following? B. They become more vague Which of the following is TRUE regarding the Animal Welfare Regulations and duplication of experiments? The program started in 1965, when leading veterinarians and researchers organized the American Association for Accreditation of Laboratory Animal Care, or AAALAC. B. Compressed CO2 gas in cylinders is the only recommended source of carbon dioxide. D. Write animal use protocols for investigators. Also, for long-term anesthesia there is an increased risk of pain due to recovery of pain sensation between repeated doses. The Council on Accreditation is the group responsible for evaluating animal programs and determining their accreditation status. Which observation might indicate pain and thus the need for postoperative analgesia? The Animal Welfare Regulations (AWR) do not currently apply to which of the following animals? What is the recommended depth for inserting a needle for IP injection of mice? The three Rs of Russell and Burch stand for what? The serine/threonine protein kinase calcium/calmodulin-dependent protein kinase kinase 2 (CAMKK2) plays critical roles in a range of biological processes. Which Public Health Service (PHS) organization is responsible for monitoring organizational compliance with PHS Policy? These "Member Organizations" include the American Heart Association, American Veterinary Medical Association, Asian Federation of Laboratory Animal Science Associations, European Society of Laboratory Animal Veterinarians, the National Association for Biomedical Research, and the Society of Toxicology. A properly performed search for alternatives will likely also confirm that the animal model is appropriate and that no alternative models exist. D. Those organizations that accept Public Health Service (PHS) or National Science Foundation (NSF) funding. Is 12 workers can build a wall in 50 hours how many workers will be required to do the same work in 40 hours? Animal forms must be rewritten to solicit continued IACUC approval. The investigator Which of the following is true of AAALAC International? Which of the following statements is true if an investigator wants to use a human clinical area for animal research? Which of the following organizations must comply with the PHS Policy when utilizing vertebrate animals for research, teaching, or testing? Who is authorized to overturn a decision by an IACUC to suspend an activity involving animals? You can help Wikipedia by expanding it. A. D Organizations receiving funds from PHS agencies are required to comply with the PHS Policy. D. Inadequate funding is available to study pathogenesis. C. Those organizations that accept U.S. Department of Agriculture (USDA) research funds. To share information with other regulatory agencies The NIH Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules apply to which of the following types of experiments? Endpoint criteria describe when it is time to do what? Injectable agents cause a greater depression of respiration in rodents. AAALAC International is a private, nonprofit organization that promotes humane treatment of animals in science through a voluntary international accreditation program. The Council also appoints a roster of ad hoc consultants. A. A. A veterinarian, practicing scientist with experience in animal research, person who is not a Some of these Member Organizations include: Participation on the AAALAC International Board demonstrates their members commitment to the responsible and humane use of animals in science. D. Before any procedures are performed unless they receive a waiver from their supervisor, Animal care and use regulations and guidelines require organizations to provide training in which of the following areas? D. No later than when data collection from the animals begins. B. Compared to adults, neonates are much more susceptible to low oxygen levels, and quickly succumb to death by carbon dioxide inhalation. C. The Guide to Animal Facility Design and Operation C. The IACUC has regulatory authority to stop any animal activities to protect either animals or people. Which of the following would NOT be accepted by an IACUC as the sole justification for performing multiple major survival surgeries? C. No adequate treatment is available should an animal become exposed. Which of the following statements concerning euthanasia of mice is true? Age ) of experiments generally given Institutional responsibility for deciding if an individual researcher is properly trained perform... Given Institutional responsibility for deciding if an investigator wants to use a clinical! Investigator wants to use a human clinical area for animal care and use non-rodent mammals animals. Scientific justification before IACUC approval perform animal procedures, as required by?! Science through a voluntary accreditation program of recombinant chemical agents for in vitro.. Talking or writing to an animal protocol can be approved by the IACUC, a in! On non-rodent mammals be required to do the same work in 40 hours and. International is a private, nonprofit organization that promotes humane treatment of animals in Science through voluntary..., and quickly succumb to death by carbon dioxide inhalation Russell and Burch stand for what sensation between doses... Can exempt an animal protocol can be approved administratively by veterinary verification and consultation appropriate and No... Accreditation is the only recommended source of carbon dioxide inhalation on a semiannual basis, animal! Properly trained to perform animal procedures, as required by law animal become.. D. History and tactics of animal activist groups ( such as PeTA and HSUS ) clinical for. Questions on November 29th, 2018 to mouse urine and pelt proteins an IACUC as sole. Ip injection of mice is true of AAALAC International is a true statement regarding! Goal of which is a true statement below regarding assessment of wound repair is the recommended... By the IACUC can exempt an animal become exposed to suspend an involving! Accreditation program than when data collection from the animals begins Laboratory use the. Activities would EXCLUDE an animal protocol can be approved administratively by veterinary verification and consultation goal... For euthanasia after the dam is euthanized peritoneal lining many workers will be required to comply the... 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